In women, the ovaries produce the female hormones estrogen and progesterone. Estrogen and progesterone control a woman's periods and other processes in her body. As a woman approaches menopause, her ovaries gradually makes less and less of these hormones. A hot flash is a feeling described as suddenly being hot, flushed and uncomfortable, especially in the face and neck. Hot flashes come in bursts or flushes that usually last a few seconds to a few minutes. They are caused by changes in the way blood vessels relax and contract and are thought to be related to the changes in a woman's estrogen levels. A woman can have irregular periods for several months to years before her periods finally stop. Any vaginal bleeding that develops after a year of no periods is abnormal and should be evaluated by a doctor. Sleep often is disturbed by nighttime hot flashes. A long-term lack of sleep can lead to changes in moods and emotions. The chemical changes that happen during menopause do not increase the risk of depression. However, many women experience major life changes during their middle age including menopause and sleep disturbances, which can increase the risk of developing depression. As estrogen levels drop and remain low during menopause, the risk of developing osteoporosis increases. The risk is greatest for slender, white or light-skinned women. You can help prevent osteoporosis by getting enough vitamin D through sunlight or a daily multivitamin, eating a diet rich in calcium and performing regular exercise. Women should start taking these actions well before menopause begins. This is because women begin to lose bone mass as early as age 30 but fractures resulting from osteoporosis don't occur until 10 to 15 years after menopause. For most women, the diagnosis of menopause is made based on a woman's description of her symptoms and the ending of her menstrual periods. Laboratory testing is not usually needed. However, recent evidence has shown that there are some risks associated with the use of these medicines. Estrogen therapy can increase the risk of heart disease, stroke, breast cancer and blood clots in a small number of women. On the other hand, it prevents fractures and can decrease the risk of colon cancer. Therefore, the decision to use hormone replacement therapy to treat symptoms of menopause is an individual decision. A woman should talk to her doctor about the risks and benefits of hormone replacement therapy for her. The Gabapentin (Neurontin) moderately effective in treating hot flashes. Gabapentin's main side effect is drowsiness. Taking it at bedtime may help improve sleep while decreasing hot flashes. All postmenopausal women who have osteoporosis or are at risk of osteoporosis should take calcium and vitamin D supplements. The usual recommended supplemental dose is 1,000 milligrams of calcium carbonate (taken with meals) or calcium citrate daily. It is best to take this as 500 milligrams twice a day. Women also need 800 international units of vitamin D daily. There is no relation between the time of a woman's first period and her age at menopause. The age at menopause is not influenced by a woman's race, height, number of children or use of oral contraceptives.
Menstrual cycling in women results from a complex interplay of reproductive hormones that surge and ebb at various points during the course of an approximately lunar month (28 days). Research shows that diet and nutrition play a significant role in the severity of PMS symptoms, and many women could ease their monthly bouts with discomfort simply by changing their diets or taking nutritional supplements. Many women with premenstrual syndrome have high sugar and high dairy fat intakes, both of which lower magnesium values in the blood. Supplemental magnesium appears to be a necessity, particularly in persons who are getting little magnesium from their water. PMS-sufferers are also frequently deficient in calcium, zinc and B-vitamins, particularly vitamin B6, and can often benefit greatly from supplementation. Experts still aren't sure exactly what causes PMS. Some research shows that it's related to hormonal changes that occur during a woman's menstrual cycle. The symptoms may arise during ovulation or just before menses, or they may appear, disappear and reappear during the same cycle. For about one in 20 women, the combination is so bad that it creates a general depression that affects the daily course of their lives. A deficiency of progesterone can exacerbate symptoms of premenstrual syndrome (PMS) and menopausal discomforts, and may increase the risk of osteoporosis. It is caused by normal changes in breast tissue related to monthly fluctuations in levels of estrogen and progesterone, which cause the glands and ducts in the breast to enlarge. As a result, the breasts become swollen, painful, tender, and lumpy. For many women, these symptoms occur as part of the premenstrual syndrome and usually disappear during or after menstruation.

Terms on this pageAnxiety
- A state of uneasiness and apprehension, as about future uncertainties.
- Worry or tension in response to real or imagined stress, danger, or dreaded situations. Physical reactions such as fast pulse, sweating, trembling, fatigue, and weakness may accompany anxiety.
Chlorella
- Chlorella is a genus of single-celled green algae, belonging to the phylum Chlorophyta. It is spherical in shape, about 2 to 10 nm in diameter, and is without flagella. Chlorella contains the green photosynthetic pigments chlorophyll-a and -b in its chloroplast. It depends on photosynthesis for growth and multiplies rapidly, requiring only carbon dioxide, water, sunlight, and a small amount of minerals..
Estrogen
- Any one of a group of hormones synthesized by the reproductive organs and adrenal glands in females and, in lesser quantities, in males. The estrogens cause the thickening of the lining of the uterus and vagina in the early phase of the ovulatory, or menstrual, cycle; in lower animals cyclical estrogen secretion also induces estrus, or "heat". The estrogens are also responsible for female secondary sex characteristics such as, in humans, pubic hair and breasts, and they affect other tissues including the genital organs, skin, hair, blood vessels, bone, and pelvic muscles..
Menopause
- The period marked by the natural and permanent cessation of menstruation, occurring usually between the ages of 45 and 55.
PMS
Perimenopause
- The time period prior to menopause that may last 10 to 15 years, even beginning in one's 30s. It is associated with decreased ovarian function and decreasing estrogen levels.
Progesterone
- Steroid hormone secreted by the female reproductive system that functions mainly to regulate the condition of the endometrium (see uterus), preparing it to accept a fertilized egg. If the egg is not fertilized, the level of progesterone drops, the uterine lining breaks down, and menstruation ensues. If the egg is fertilized, the placenta produces progesterone, whose effects include preparing the mammary glands for lactation..
Biopsy
- Bone marrow aspiration, also called bone marrow sampling, is the removal by suction of fluid from the soft, spongy material that lines the inside of most bones. Bone marrow biopsy, or needle biopsy, is the removal of a small piece of bone marrow.
Climacteric
- A period of life characterized by physiological and psychic change that marks the end of the reproductive capacity of women and terminates with the completion of menopause.
- A corresponding period sometimes occurring in men that may be marked by a reduction in sexual activity, although fertility is retained.
Depression
- In psychiatry, a symptom of mood disorder characterized by intense feelings of loss, sadness, hopelessness, failure, and rejection.
Estrogen
- Any one of a group of hormones synthesized by the reproductive organs and adrenal glands in females and, in lesser quantities, in males.
Hormone
- A substance, usually a peptide or steroid, produced by one tissue and conveyed by the bloodstream to another to effect physiological activity, such as growth or metabolism.
Osteoporosis
- A disease in which the bones become extremely porous, are subject to fracture, and heal slowly, occurring especially in women following menopause and often leading to curvature of the spine from vertebral collapse.
Premenstrual syndrome
- The syndrome occurs in several distinct forms: emotional upheaval, including anxiety, irritability, insomnia, depression, forgetfulness, confusion, and lethargy; cravings for sweets, increased appetite, and intolerance to sugar (headache, heart palpitations, fatigue, and fainting); and fluid retention symptoms with weight gain, puffiness of hands and feet, breast swelling and tenderness, and abdominal bloating and tenderness. Some women suffer with symptoms of all these forms, others only a few..
Progesterone
- A drug prepared from natural or synthetic progesterone, used in the prevention of miscarriage, in the treatment of menstrual disorders, and as a constituent of some oral contraceptives.
- A female hormone that acts on the inner lining of the uterus and prepares it for implantation of the fertilized egg.
Stress
- A state of extreme difficulty, pressure, or strain.
- A physical and psychological response that results from being exposed to a demand or pressure.
Testosterone
- A white crystalline steroid hormone, C19H28O2, produced primarily in the testes and responsible for the development and maintenance of male secondary sex characteristics. It is also produced synthetically for use in medical treatment.
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